August 2024, Vol 81, No. 8, Pages 788-889

This cross-sectional study assesses maternal history or paternal history of memory impairment (as a proxy for Alzheimer disease dementia) and brain β-amyloid burden and cognition in older adults.

This cohort study of patients in Denmark with atrial fibrillation investigates whether discontinuation of oral anticoagulation is associated with an increased risk of recurrent ischemic stroke.

This cohort study evaluates clinical events identified as relapses not associated with T2 lesions or gadolinium-enhanced T1 lesions on magnetic resonance imaging.

This cohort study evaluates associations of sleep and 24-hour activity rhythms with amyloid-β deposition.

This cohort study assesses rates of thromboembolic events in adults with atrial fibrillation (AF) and epilepsy receiving direct-acting oral anticoagulants (OACs) and enzyme-inducing antiseizure medications (ASMs) vs direct-acting OACs with non–enzyme-inducing ASMs.

This cohort study evaluates the use of tau positron emission tomography in estimating risk of progression to dementia in individuals with mild cognitive impairment.

This randomized clinical trial analyzes data for children with central nervous system malaria whose fever was treated aggressively with preemptive acetaminophen and ibuprofen to assess reduction in maximum temperature vs that achieved with usual care.

This cohort study uses propensity score matching to evaluate the association of angiotensin receptor blockers use with risk of incident epilepsy compared with other antihypertensive drugs in subgroups of US patients with hypertension.

This cohort study assesses the derivation and validation of International Statistical Classification of Diseases, Tenth Revision (ICD-10) codes in detecting incident stroke events in Medicare inpatient fee-for-service claims data.