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Caring for the Critically Ill Patient

Explore JAMA’s influential critical care medicine series, including new guidelines, important clinical trials, and more on topics such as sepsis and respiratory failure and ventilation.

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JAMA

Medical News in Brief

A New Assay Might Speed Antimicrobial Susceptibility Testing in Sepsis

Samantha Anderer

A Piece of My Mind

Bittersweet Prognostication

Lauren Rissman, MD

Medical News & Perspectives

A Surge in Ransomware Attacks Threatens Health Systems and Patient Care

Anna Bock

Medical News & Perspectives

Using “Power Prescriptions” to Counter Energy Insecurity

Anika Nayak

Editorial

SGL-2 Therapy for Acute Organ Dysfunction

Hernando Gómez, MD, MPH, Lennie P. G. Derde, MD, PhD

Original Investigation

Dapagliflozin in Critically Ill Patients With Acute Organ Dysfunction

Caio A. M. Tavares, MD, PhD, Luciano C. P. Azevedo, MD, PhD et al.

Original Investigation

Prolonged vs Intermittent Infusions of β-Lactam Antibiotics in Adults With Sepsis or Septic Shock

Mohd H. Abdul-Aziz, BPharm, PhD, Naomi E. Hammond, RN, PhD et al.

Original Investigation

Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis

Joel M. Dulhunty, MD, PhD, Stephen J. Brett, MD et al.

Editorial

Resolving the Dilemma on Continuous vs Intermittent β-Lactam Antibiotics in Sepsis

W. Joost Wiersinga, MD, PhD, MBA, Michiel A. van Agtmael, MD, PhD

Review

Low-Dose Corticosteroids for Adults With Severe Pulmonary Infections

Romain Pirracchio, MD, MPH, PhD, Balasubramanian Venkatesh, MD et al.

Viewpoint

Failure to Rescue as a Quality Measure in Sepsis

Stephanie Parks Taylor, MD, MS, Marc Kowalkowski, PhD

A Piece of My Mind

The Other Side of the Curtain

Paige Stevens, MD

Original Investigation

Acetaminophen for Prevention and Treatment of Organ Dysfunction

Lorraine B. Ware, MD, D. Clark Files, MD et al.

Original Investigation

Stewardship Prompts to Improve Antibiotic Selection for Pneumonia

Shruti K. Gohil, MD, MPH, Edward Septimus, MD et al.

A Piece of My Mind

Good Enough

Lauren Rissman, MD

Research Letter

Cardiac Function Before Sepsis and Clinical Outcomes

Stuthi Iyer, MPH, Jason N. Kennedy, MS et al.

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JAMA NETWORK

Original Investigation

Antithrombin III Levels and Outcomes Among Patients With Trauma

David H. Farrell, PhD, Keeley M. McConnell, BS et al.

JAMA Network Open |

Original Investigation

Umbilical Cord pH Levels and Neonatal Morbidity and Mortality

Charlotte Brix Andersson, MD, Claus Klingenberg, PhD et al.

JAMA Network Open |

Original Investigation

CPAP Treatment and Hypertensive Adverse Outcomes in Pregnancy

Yi-Chieh Lee, MD, MSc, Yun-Chen Chang, MD et al.

JAMA Network Open |

Original Investigation

Interrupted vs Continuous Sedation in Mechanically Ventilated Patients

Theresa Shu Wen Toh, MBBS, MRCPCH, Pravin R. R., MBBS, MRCPCH et al.

JAMA Network Open |

Original Investigation

Characteristics of Pediatric In-Hospital Cardiac Arrests and Resuscitation Duration

Amanda O’Halloran, MD, Ryan W. Morgan, MD, MTR et al.

JAMA Network Open |

Original Investigation

Neonatal Sepsis Episodes and Retinopathy of Prematurity in Very Preterm Infants

Kirsten Glaser, MD, Christoph Härtel, MD et al.

JAMA Network Open |

Original Investigation

Sepsis Alert Systems, Mortality, and Adherence in Emergency Departments

Hyung-Jun Kim, MD, Ryoung-Eun Ko, MD et al.

JAMA Network Open |

Inside Story

Life and Death—Ask. Do Not Assume

Anirudh Yalamanchali, MD, MS

JAMA Internal Medicine |

Viewpoint

Neuroimaging-Guided Music Interventions for Infants in NICU

Efthymios Papatzikis, PhD

JAMA Pediatrics |

Editorial

Hospital-Onset Bacteremia—Counting Them All

Karen M. Puopolo, MD, PhD

JAMA Pediatrics |

Original Investigation

Barriers and Opportunities for Adapting Critical Care Clinical Trials in the Pandemic

Deborah Cook, MD, MSc, Shipra Taneja, BSc, MSc et al.

JAMA Network Open |

Original Investigation

Termination of Resuscitation Rules and Survival in Out-of-Hospital Cardiac Arrest

Michael A. Smyth, PhD, Imogen Gunson, MSc et al.

JAMA Network Open |

Invited Commentary

Optimizing the Value of β-Lactam Antibiotics Through Extended Infusion

Miranda So, PharmD, MPH

JAMA Network Open |

Original Investigation

Outcomes Among Hospitalized Adults Receiving Extended-Infusion β-Lactam Therapy

Sara M. Karaba, MD, PhD, MHS, Sara E. Cosgrove, MD, MS et al.

JAMA Network Open |

Original Investigation

Factors Associated With Quality of Dying and Death Among Critically Ill Patients

Fur-Hsing Wen, PhD, Wen-Chi Chou, MD et al.

JAMA Network Open |

Original Investigation

Empiric Broad-Spectrum Antibiotic Use for Suspected Community-Onset Sepsis in US Hospitals

Chanu Rhee, MD, MPH, Tom Chen, PhD et al.

JAMA Network Open |
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